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A 17-year-old boy is brought to the emergency department by ambulance 30 minutes after the sudden onset of weakness in his legs and upper arms. He explains that he has been under a lot of stress lately preparing for a set of important exams. He had a similar episode 7 months ago the first night after finishing a football tournament with his high school. At the time, the weakness lasted 5 hours and resolved completely without treatment. At follow-up examination 1 week later, the results of a complete blood count, routine serum studies, and an MRI of the brain and spine showed no abnormalities. Medical and family history is otherwise unremarkable. He is not sexually active. He takes no medications and his immunizations are up-to-date. He smokes 2–3 cigarettes daily and does not drink alcohol or use illicit drugs. He is 180 cm (5 ft 11 in) tall and weighs 75 kg (165 lb); BMI is 23 kg/m². Temperature is 36.5°C (97.7°F), pulse is 75/min, respirations are 18/min, and blood pressure is 135/85 mm Hg. Pulse oximetry on room air shows an oxygen saturation of 99%. Muscle strength is 2/5 in the hip flexors and knee extensors, 3/5 in the shoulder abductors, and 4/5 in all other muscle groups. Deep tendon reflexes are 1+ throughout. Sensation is intact. He is oriented to person, place, and time. Examination of the cranial nerves shows no abnormalities. Cardiopulmonary examination shows no other abnormalities. Fingerstick blood glucose concentration is normal. ECG is shown. Which of the following is the most likely diagnosis?

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Neurology Neuromuscular Disorders